{"product_id":"amiela-nad-supplement","title":"AMIELA NAD Supplement","description":"\u003cp\u003eAdvanced Cellular Longevity Support —\u003cbr\u003e\nAMIELA NAD Supplement is a next-generation formulation designed to target one of the fundamental drivers of aging: cumulative DNA damage. It provides a comprehensive approach through DNA repair support, senescent cell clearance, and inflammation modulation.\u003c\/p\u003e\n\n\u003cp\u003e01｜DNA Damage Repair Support\u003c\/p\u003e\n\n\u003cp\u003eDNA, present in every cell, serves as the fundamental blueprint for maintaining physiological function. However, it is continuously exposed to damage from cell division, UV radiation, inflammation, and infections.\u003cbr\u003e\nCellular repair mechanisms—primarily mediated by NAD+-dependent enzymes such as sirtuins and PARPs—play a critical role in maintaining genomic stability.\u003cbr\u003e\nAMIELA contains a high concentration of Nicotinamide (NAM), a key precursor that supports intracellular NAD+ production and enhances these repair pathways.\u003c\/p\u003e\n\n\u003cp\u003e02｜Senescent Cell Clearance (Senolytic Approach)\u003c\/p\u003e\n\n\u003cp\u003eSenescent cells accumulate with age and secrete pro-inflammatory factors known as SASP (Senescence-Associated Secretory Phenotype), which can accelerate tissue aging.\u003cbr\u003e\nThese dysfunctional cells are naturally cleared through immune activity and autophagy, the body’s intrinsic cellular recycling system.\u003cbr\u003e\nAMIELA includes polyphenols known to support autophagic processes, promoting the efficient clearance of senescent cells.\u003c\/p\u003e\n\n\u003cp\u003e03｜Reduction of Inflammaging (SASP Modulation)\u003c\/p\u003e\n\n\u003cp\u003eChronic, low-grade inflammation—often referred to as “inflammaging”—is a key contributor to aging and age-related conditions.\u003cbr\u003e\nSASP, along with lifestyle factors and infections, contributes to this persistent inflammatory state.\u003cbr\u003e\nAMIELA is formulated with compounds that help modulate inflammatory responses and support systemic balance.\u003c\/p\u003e\n\n\u003cp\u003eContents: 60 capsules\u003cbr\u003e\nRecommended Dosage: Take 1–2 capsules\u003c\/p\u003e","brand":"EBISUNOBUCLINIC","offers":[{"title":"Default Title","offer_id":43225902809206,"sku":null,"price":999999.0,"currency_code":"JPY","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0608\/4853\/7718\/files\/NADSupplementProduct_8fa8650a-bdf2-46e8-a5d9-754390d6eb27.jpg?v=1774407426","url":"https:\/\/ebisunobuclinic.us\/products\/amiela-nad-supplement","provider":"EBISUNOBUCLINIC INTL","version":"1.0","type":"link"}